| 产品详情 |
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| Product Name | N-Octadecyl-N'-propyl-sulfamide |
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| Description | Purity >95%. Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARAlpha, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally. N-Octadecyl-N'-propyl-sulfamide is an analog of OEA with selective binding affinity for PPARAlpha. It is a more potent activator of PPARAlpha, exhibiting an EC50 value of 100 nM, compared to OEA, which exhibits an EC50 value of 120 nM. At a dose of 1 mg/kg for 8-11 days, N-octadecyl-N'-propyl-sulfamide induces satiety, thereby decreasing food-intake, body weight, and plasma triglyceride concentration in free-feeding Wistar and obese Zucker (fa/fa) rats. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-octadecyl-N'-propyl-sulfamide |
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| Gene, Accession, CAS # | CAS: 925891-74-3 |
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| Catalog # | LS-H9037 |
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| Order / More Info | N-Octadecyl-N'-propyl-sulfamide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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