| 产品详情 |
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| Product Name | AS-041164 |
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| Description | MW: 249.2. Purity 98% (TLC); NMR (Conforms). PI3Kgamma InhibitorPotent and selective protein kinase C inhibitor with specificity for the and 1 isotypes. IC50=0.0084, 0.018, 0.210, 0.132 and 0.58 M for, 1,,, and respectively1. An extremely useful tool for assessing the involvement of PKC in various signaling pathways2,3.Scientific Background: A selective PI 3-Kgamma isoform inhibitor (IC50 = 0.24, 1.45, 0.07 and 1.70 uM for alpha, beta, gamma and delta isoforms respectively). B |
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| Size | 10 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [GF-109203X ; 2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl) maleimide; Bisindolylmaleimide I] |
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| Gene, Accession, CAS # | CAS: 6318-41-8 |
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| Catalog # | MBS515050 |
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| Order / More Info | AS-041164 from MYBIOSOURCE INC. |
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| Product Specific References | D Toullec et al. J. Biol. Chem. 1991 266:15771 2. T Bouschet et al. J. Biol. Chem. 2003 278:4778 3. G Robert et al. PLoS One 2009 4:e7889 |
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