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| Product Name | Guanabenz Acetate (WY-8678, 1-(2,6-Dichlorobenzylideneamino)guanidine, Acetate) |
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| Description | Purity ~99% (HPLC). A cell-permeable a2-adrenoceptor agonist that lowers protein misfolding in stressed cells (EC50 ~400nM in tunicamycin treated HeLa cells) and acts as a proteostatis regulator. Shown to selectively bind PPP1R15A/GADD34 and disrupt the PPP1R15A-PP1c complex; sustain eIF2a phosphorylation and increase chaperone availability by attenuating translation. Formula: C8H8Cl2N4•C2H4O2 Molecular Weight: 291.1 Solubility: H2O (5mg/ml) |
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| Size | 250mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217407 |
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| Order / More Info | Guanabenz Acetate (WY-8678, 1-(2,6-Dichlorobenzylideneamino)guanidine, Acetate) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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