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| Product Name | Goserelin, Human |
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| Description | Purity ~ 95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. Goserelin has actions similar to those of naturally occurring LHRH. LHRH released from the hypothalamus stimulates receptors on the pituitary gland, which then releases the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Goserelin and other LHRH agonists provide a medical castration that deprives hormonally-dependent tumors of testosterone or estrogen. Normally, LHRH is released in a pulsatile manner to maintain levels of gonadotropins. Goserelin, in contrast, is continuously administered, which leads to downregulation of the LHRH receptor on the pituitary gland and decreased production of FSH and LH. During short-term or intermittent treatment, goserelin has the same stimulatory action as LHRH. This stimulation produces a surge of FSH and LH, which can cause a flare reaction in patients with prostate or breast carcinoma. Sequence: Glu-His-Trp-Ser- |
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| Size | 5mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G8578-90 |
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| Order / More Info | Goserelin, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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