| 产品详情 |
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| Product Name | Recombinant Human N-glycosylase/DNA lyase |
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| Description | 1-345aa; Full Length. MW: 42.05kD. Purity >90% as determined by SDS-PAGE. DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Including the following 2 domains: 8-oxoguanine DNA glycosylase (EC:3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC:4.2.99.18); AP lyase] |
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| Gene, Accession, CAS # | OGG1, Gene ID: 4968, Accession: NP_002533.1 |
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| Catalog # | MBS1151639 |
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| Order / More Info | Recombinant Human N-glycosylase/DNA lyase from MYBIOSOURCE INC. |
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| Product Specific References | Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. Aburatani H., Hippo Y., Ishida T., Takashima R., Matsuba C., Kodama T., Takao M., Yasui A., Yamamoto K., Asano M., Fukasawa K., Yoshinari T., Inoue H., Otsuka E., Nishimura S. Cancer Res. 57:2151-2156(1997) |
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