产品详情 |
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Product Name | Loperamide hydrochloride |
Description | High affinity μ-opioid receptor agonist with peripheral selectivity (Ki values are 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca2+ channels and at higher concentrations it reduces Ca2+ flux through NMDA receptor operated channels. Purity 99%. MW (observed): 513.51 |
Size | 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide hydrochloride |
Gene, Accession, CAS # | CAS: 34552-83-5 |
Catalog # | 0840/1G |
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Order / More Info | Loperamide hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 26068703 |
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