| 产品详情 |
| Edit |   |
|---|
| Product Name | Pyruvate Kinase, Isozymes M1/M2 Control Peptide |
|---|
| Description | Highly Purified (~95%) . Control Peptide for P9545-31M. Pyruvate kinase is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, yielding a pyruvate molecule. There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells. Human PKM1/2 is 531aa protein. Human PKM2 389-433aa (IYHLQLFEELRR LAPITSDPTE ATAVGAVEASFKCCSGAIIVLTK) is replaced by (MFHRKLFEELVRASSHSTDLMEAMA MGSVEASYKCLAAAL IVLTE) in PKM1. The PKM2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence. Source: Synthetic peptide corresponding to 16aa of human PK-M1/M2 (Accession # P14618), |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | Pyruvate Kinase, Isozymes M1/M2 Control Peptide (PKM2, Pyruvate Kinase Muscle Isozyme, Cytosolic Thyroid Hormone-binding Protein, CTHBP, Opa-interacting Protein 3, OIP-3, Pyruvate Kinase 2/3, Thyroid Hormone-binding Protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3) |
|---|
| Gene, Accession, CAS # | SwissProt: P14618 |
|---|
| Catalog # | P9545-31N |
|---|
| Price | |
|---|
| Order / More Info | Pyruvate Kinase, Isozymes M1/M2 Control Peptide from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|