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| Product Name | CD83, Fc Chimera, Recombinant, Human (B Cell activation protein, BL11, Cell Surface Protein HB15) |
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| Description | Purity ≥ 90%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin: ≤1.0 EU/ug (LAL). Human CD83 is a 40-50kD member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins (1, 2, 3). CD83 is synthesized as a type I transmembrane glycoprotein that contains a 125aa extracellular region, a 22 aa transmembrane segment, and 39aa cytoplasmic domain. It contains one V type Ig-like domain in the extracellular region with no inhibitory cytoplasmic motif(s). Although in vitro studies suggest CD83 may form membrane-bound covalent homodimers, in vivo this does not appear to be the case (1, 4). In the extracellular region, mouse and human CD83 are 66% aa identical (1, 2, 4, 5). Relative to human, mouse CD83 is 11 aa shorter in its extracellular domain and is expressed as a 30-35kD protein (1, 4, 5). Human CD83 is active in the mouse system (4). One alternate splice form has been reported. This leads to a small monomeric soluble form of 74aa |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 9308, SwissProt: Q01151 |
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| Catalog # | C2435-03 |
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| Order / More Info | CD83, Fc Chimera, Recombinant, Human (B Cell activation protein, BL11, Cell Surface Protein HB15) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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