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| Product Name | FGF-21(L174P), Recombinant, Human, aa29-209 (Fibroblast Growth Factor 21) |
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| Description | Purity ~90% (SDS-PAGE). FGF-21 is a unique member of FGF super family that is reported to be primarily produced by the liver. FGF-21 has recently been shown to have beneficial effects on a variety of metabolic parameters, including glucose and lipid metabolism and insulin sensitivity in animal models and is thought to exert potent antidiabetic and lipid- lowering agent of obesity and type 2 diabetes mellitus. FGF-21 activity depends on membrane protein beta Klotho that physically complexes with various FGF receptors, thus conferring them the ability to bind FGF-21 and activate downstream signaling pathways. Source: Recombinant protein corresponding to aa29-209 from human FGF-21, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~21.6kD (202aa) (confirmed by MALDI-TOF) (molecular weight on SDS-PAGE will appear higher) AA |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_061986 |
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| Catalog # | 470229 |
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| Order / More Info | FGF-21(L174P), Recombinant, Human, aa29-209 (Fibroblast Growth Factor 21) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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