产品名称 RGFP966 from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H9695
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameRGFP966
DescriptionPurity >98%. HDAC3 is highly expressed in brain, and its activity has been associated with negative regulation of learning and memory processes. RGFP966 is a selective inhibitor of HDAC3 (IC50 = 0.08 µM) that does not affect other HDACs at concentrations up to 15 µM. At 10 mg/kg, RGFP966 can facilitate the extinction of cocaine-seeking behavior and enhance long-term object memory acquisition/consolidation in mice. At 10 µM, RGFP966 can also induce apoptosis of cutaneous T cell lymphoma cells by disrupting their DNA replication activity.
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Other Names(2E)-N-(2-amino-4-fluorophenyl)-3-[1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide
Gene, Accession, CAS #CAS: 1357389-11-7
Catalog #LS-H9695
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Order / More InfoRGFP966 from LIFESPAN BIOSCIENCES INC.
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