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| Product Name | RGM-A, ELISA BioAssay™ Kit (Repulsive Guidance Molecule A, RGM Domain Family Member A, Rgma) |
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| Description | Mouse Repulsive Guidance Molecule (RGM-A) is a 33kD member of the RGM family of GPI-linked membrane associated proteins (1, 2). It is synthesized as a 454aa prepro-protein that contains a 47aa N-terminal signal sequence and a 27aa C-terminal GPI attachment signal (3, 4). As a result of intramolecular cleavage, mature mouse RGM-A is a disulfide-linked dimer of the 122aa N-terminal and 258 C-terminal segments. The N-terminal segment contains an RGD tripeptide and two potential N-linked glycosylation sites, while the C-terminal segment contains an abbreviated von Willebrand factor domain (3-5). Mouse RGM-A shares 86%, 94%, and 100% aa sequence identity with chicken, human, and rat RGM-A, respectively. It also shares 56-48% aa sequence identity with RGM-B and -C, respectively. RGM-A is expressed in the developing central nervous system in a pattern that is complementary to the expression of RGM-B (3, 4). It is widely expressed on neuronal and glial cells of the mouse nervous system, partic |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | R1994-87 |
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| Order / More Info | RGM-A, ELISA BioAssay™ Kit (Repulsive Guidance Molecule A, RGM Domain Family Member A, Rgma) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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