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Product Name | Fetuin B (FETUB) (AA 16-382) protein (His tag) |
Description | Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20% amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.Alternative Names: Fetuin-B, 16G2, Fetuin-Like Protein IRL685, Gugu, FETUB |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | gugu|fetuin-b|FETUB|16g2|irl685|im:6910148|16G2|Gugu|IRL685|Fet|Pp63|2310011O17Rik|AI255764|D17980 |
Gene, Accession, CAS # | Gene ID: 26998 |
Catalog # | ABIN1096645 |
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Order / More Info | Fetuin B (FETUB) (AA 16-382) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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