| 产品详情 |
| Edit |   |
|---|
| Product Name | SPHK1, Active |
|---|
| Description | Full length. MW: ~71 kDa. Description: Recombinant full-length human SPHK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP) which is a novel lipid messenger with both intracellular and extracellular functions. Various stimuli increase cellular levels of SPP by activation of SPHK1 (1). Competitive inhibitors of SPHK1 block formation of SPP and selectively |
|---|
| Size | 0.005 mg, 0.01 mg |
|---|
| Concentration | n/a |
|---|
| Applications | Kinase Assay |
|---|
| Other Names | [Homo sapiens sphingosine kinase 1, mRNA; Sphingosine kinase 1; sphingosine kinase 1; sphingosine kinase 1] |
|---|
| Gene, Accession, CAS # | SPHK1 , Gene ID: 8877, Accession: BC008040 |
|---|
| Catalog # | MBS515664 |
|---|
| Price | |
|---|
| Order / More Info | SPHK1, Active from MYBIOSOURCE INC. |
|---|
| Product Specific References | 1. Xia, P. et al: Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling. J. Biol. Chem. 2777996-8003, 2002. 2. Pappu, R. et al: Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 316295-298, 2007. |
|---|
| 产品资料 |
|
|