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| Product Name | SPHK2, Active |
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| Description | Full length. MW: ~110 kDa. Description: Recombinant full-length human SPHK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: SPHK2 is a member of the SPHK family and catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P). Sphingolipid metabolism regulates proper uterine decidualization and blood vessel stability (1). SPHK2 is involved in the regulation of chemosensitivity by control |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 1, mRNA; Sphingosine kinase 2; sphingosine kinase 2; sphingosine kinase 2] |
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| Gene, Accession, CAS # | SPHK2 , Gene ID: 56848, Accession: NM_020126.4 |
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| Catalog # | MBS515665 |
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| Order / More Info | SPHK2, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Mizugishi, K. et al: Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice. J. Clin. Invest. 1172993-3006, 2007. 2. Hait, N. C.et al: Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science 3251254-1257, 2009. NoteErratumScience 326366 only, 2009. |
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