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| Product Name | Melanoma Inhibitory Activity Protein, Recombinant, Human (MIA) |
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| Description | Purity ≥95% by RP-HPLC or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors, including gliomas, in an autocrine fashion. In a study of human melanoma cell lines with different metastatic capacity MIA mRNA expression appeared to be inversely correlated with pigmentation. MIA has been shown to represent a very sensitive and specific serum marker for systemic malignant melanoma that might be useful for staging of primary melanomas, detection of progression from localized to metastatic disease during follow-up, and monitoring therapy of advanced melanomas. Recombinant Human MIA is a single, non-glycosylated, polypeptide chain consisting of 108aa having a total molecular mass of 12237 Dalton. The Melanoma Inhibitory protein (MIA) was identified as an inhibitor of in vitro growth of malignant melanoma cells. The protein contains a SH3 domain. Amino Acid |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M2869-95 |
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| Order / More Info | Melanoma Inhibitory Activity Protein, Recombinant, Human (MIA) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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