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Product Name | Sarsasapogenin |
Description | A steroid sapogenin; inhibits proliferation of HeLa cervical, MCF-7 breast, HepG2 liver, A549 lung, A375.S2 melanoma, and HT-1080 fibrosarcoma cells (IC50s = 31.36-48.79 µM); dose-dependently induces apoptosis of HeLa cells; protects human SH-SY5Y neuroblastoma cells from hydrogen peroxide-induced death with a neuroprotective ratio of 27.3% at 100 µM; reduces 2,3,4-trinitrobenzene sulfonic acid-induced colon shortening, myeloperoxidase activity, NF-κB activation, and IL-1β, TNF-α, and IL-6 levels in mice at 10 mg/kg; increases the percentage of correct responses in the Y-maze test in aged rats at 3.6 mg/kg per day; reduces the amount of time mice spend immobile in the forced swim test at 12.5 mg/kg per day |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 1615 |
Gene, Accession, CAS # | CAS: 126-19-2 |
Catalog # | 24973-50 |
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Order / More Info | Sarsasapogenin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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