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| Product Name | HCV-NS5a, 2210-2306aa, Hepatitis C Virus, His tag, E Coli |
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| Description | MW: 13.4 kDa (118aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. NS5A is a component of the replication complex involved in RNA-binding. Its interaction with Human VAPB may target the viral replication complex to vesicles. This protein down-regulates viral IRES translation initiation and mediates interferon resistance, presumably by interacting with and inhibiting human EIF2AK2/PKR. NS5a seems to inhibit apoptosis by interacting with BIN1 and FKBP8. The hyperphosphorylated form of NS5A is a |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Polyprotein; Hepatitis C virus non-structural 5a protein membrane anchor] |
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| Gene, Accession, CAS # | HCV-NS5a, Gene ID: 951475, Accession: NP_671491 |
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| Catalog # | MBS205638 |
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| Order / More Info | HCV-NS5a, 2210-2306aa, Hepatitis C Virus, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Taylor D.R., et al. (2001) J. Virol. 75:1265-1273; Kalliampakou K.I., et al. (2015) J. Gen. Virol. 86:1015-1025 |
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