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| Product Name | Hck, active (Hematopoietic Cellular Kinase) Recombinant, His-Tag, aa230-497 |
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| Description | Purified using Ni2+/NTA agarose. ~70% by SDS-PAGE and Coomassie blue staining. The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. Source: N-terminal His6-tagged, recombinant, human Hck, aa230-497, expressed by baculovirus in Sf21 insect cells. Specific Activity: As reported (typically >10,000U/mg). One unit of Hck activity is defined as 1nmol phosphate incorporated into 250uM Src substrate peptide (KVEKIGEGTYGVVYK) per minute at 30°C with a final ATP concentration of 100uM. Quality Control Testing: MS Tryptic Fingerprint: Confirmed identity as Hck with 6 |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002110.2, SwissProt: P08631 |
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| Catalog # | H1827A |
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| Order / More Info | Hck, active (Hematopoietic Cellular Kinase) Recombinant, His-Tag, aa230-497 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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