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| Product Name | uLBP1, 26-216aa, Human, His tag, E Coli |
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| Description | MW: 25 kDa (216aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. uLBP1 is ligand for the NKG2D receptor, together with at least uLBP2 and uLBP3. uLBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. In CMV infected cells, uLBP1 interacts with soluble CMV glycoprotein uL16. The interaction with uL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [NKG2D ligand 1; uL16 binding protein 1; RAET1I; N2DL-1; N2DL1; NKG2D ligand 1] |
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| Gene, Accession, CAS # | uLBP1, Gene ID: 80329, Accession: NP_079494 |
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| Catalog # | MBS204695 |
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| Order / More Info | uLBP1, 26-216aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Cerwenka A., et al. (2003). Tissue Antigens. 61 (5):335-43.; Bacon L., et al. (2004). J Immunol. 15;173 (2):1078-84. |
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