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| Product Name | uLBP2, 26-216aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 24.3 kDa (216aa). Purity >85% by SDS-PAGE. uLBP2, also known as NKG2D ligand 2, belongs to the MHC class I family. This protein is ligand for the NKG2D receptor, together with at least uLBP1 and uLBP3. uLBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of uLBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [NKG2D ligand 2; N2DL2; RAET1H] |
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| Gene, Accession, CAS # | uLBP2, Gene ID: 80328, Accession: NP_079493 |
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| Catalog # | MBS204457 |
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| Order / More Info | uLBP2, 26-216aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Cosman D., et al. (2001) Immunity. 14:123-133; Dunn C., et al. (2003) J. Exp. Med. 197:1427-1439 |
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