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| Product Name | Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
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| Description | 1-170aa; Full Length of Isoform 2. MW: 35.3kD. Purity >90% as determined by SDS-PAGE. Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative dethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketog |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Alkylated DNA repair protein alk; B homolog 3; DEPC-1; Prostate cancer antigen 1] |
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| Gene, Accession, CAS # | ALKBH3, Gene ID: 221120, Accession: NP_631917.1 |
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| Catalog # | MBS1301403 |
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| Order / More Info | Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 from MYBIOSOURCE INC. |
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| Product Specific References | Homo sapiens mRNA expressed in prostate cancer and thymus.Tsujikawa K., Konishi N., Ono Y., Ichijou T., Sakamoto K., Yamamoto H. NIEHS SNPs programHuman chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C |
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