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| Antigenic Specificity | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) |
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| Clone | RYNmCTLA-4 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseasesSynonyms: GSE, CD152, IDDM12, CELIAC3, CTLA-4 |
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| Immunogen | mixture of mouse activated T cells |
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| Other Names | CTLA-4|CTLA4|CD152|Cd152|Ctla-4|Ly-56|CD|CELIAC3|GRD4|GSE|IDDM12|sCTLA4 |
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| Gene, Accession # | Gene ID: 12477 |
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| Catalog # | ABIN808108 |
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| Price | |
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| Order / More Info | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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