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| Product Name | TPO, Recombinant, Human, Animal Free |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle.It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo.TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.Human and murine TPO exhibits cross-species reactivity.Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6kD), which contains the erythropoietin-like domain of the full length TPO protein. Source: Recombinant protein corresponding to human TPO, expressed in E. coli. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be 1x10e6units/mg. Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TPO, Recombinant, Human, Animal Free (Thrombopoietin, Megakaryocyte Colony-Stimulating Factor, c-MPL Ligand, MGDF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208702 |
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| Order / More Info | TPO, Recombinant, Human, Animal Free from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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