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| Product Name | TPO, Recombinant, Rat |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle.It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo.TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.Human and murine TPO exhibits cross-species reactivity.Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7kD), which contains the erythropoietin-like domain of the full length TPO protein. Biological Activity: Determined by its ability to stimulate the proliferation of human MO7e cells. The expected B>ED50 is ~0.2ng/ml, corresponding to a specific activity of ~5x10e6 units/mg. AA Sequence: SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF Crossreactivit |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TPO, Recombinant, Rat (Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143528 |
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| Order / More Info | TPO, Recombinant, Rat from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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