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| Product Name | TPO, Recombinant, Rat, Animal Free |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle.It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo.TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.Human and murine TPO exhibits cross-species reactivity.Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7kD), which contains the erythropoietin-like domain of the full length TPO protein. Source: Recombinant protein corresponding to rat TPO expressed in E. coli. Biological Activity: Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is 5x10e6units/mg. Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRL |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TPO, Recombinant, Rat, Animal Free (Rat Thrombopoietin, Megakaryocyte Colony-Stimulating Factor, c-MPL Ligand, MGDF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208703 |
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| Order / More Info | TPO, Recombinant, Rat, Animal Free from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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