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| Product Name | Immunoglobulin-Like Transcript 5, Recombinant, Human |
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| Description | Purity ≥95% by SDS-PAGE under reducing conditions and visualized with silver stain. Endotoxin:≤1EU/ug (LAL). Immunoglobulin-like transcript 5 (ILT5), also known as leukocyte immunoglobulin-like receptor subfamily B (LILRB3), leukocyte immunoglobulin-like receptor 3 (LI R3) and CD85a, is an Ig-like recept or family member that is involved in immune regulation. ILT5 belongs to subfamily B whose members have cytoplasmic tails that contain immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that inhibit signaling events via phosphatase SHP-1. The counterpart to subfamily B is subfamily A, whose members qualify as activating receptors that lack ITIMs, but signal through association with FcRg. ILTs share structural homology and chromosomal localization with the KIR family of receptors (1, 2). Mature ILT5 is a highly polymorphic 85-95kD glycoprotein that consists of a 420aa extracellular domain with four Ig-like domains, a 21aa transmembrane segment, and a 167aa cytoplasmic domain with th |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Immunoglobulin-Like Transcript 5, Recombinant, Human (ILT5, CD85a, CD85 antigen-like family member A, Leukocyte immunoglobulin-like receptor subfamily B member 3, Monocyte inhibitory receptor HL9, LILRB3, LIR3) |
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| Gene, Accession, CAS # | Accession: AAB68668 |
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| Catalog # | I7502-81 |
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| Order / More Info | Immunoglobulin-Like Transcript 5, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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