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Product Name | Recombinant Human Toll-like receptor 2 |
Description | 19-588aa; Extracellular Domain. MW: 80.4kD. Purity >90% as determined by SDS-PAGE. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes myc |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [Toll/interleukin-1 receptor-like protein 4; CD282] |
Gene, Accession, CAS # | TLR2, Gene ID: 7097, Accession: NP_003255.2 |
Catalog # | MBS1213928 |
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Order / More Info | Recombinant Human Toll-like receptor 2 from MYBIOSOURCE INC. |
Product Specific References | Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4evidence for a multi-gene receptor family in humans.Chaudhary P.M., Ferguson C., Nguyen V., Nguyen O., Massa H.F., Eby M., Jasmin A., Trask B.J., Hood L., Nelson P.S.Blood 91:4020-4027(1998) A family of human receptors structurally related to Drosophila Toll.Rock F.L., Hardiman G., Timans J.C., Kastelein R.A., Bazan J.F.Proc. Natl. Acad. Sci. U.S.A. 95:588-593(1998) Toll-like receptor-2 mediates lipopolysacch |
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