| 产品详情 |
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| Product Name | Rho Kinase Inhibitor |
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| Description | Purity ~95% (HPLC). A cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, reversible, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK; Ki=1.6nM). Inhibits other serine/threonine kinases only at higher concentrations (Ki=630nM for PKA, 9.27 uM for PKC, and 10.1uM for MLCK). Shown to selectively block lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in NT-2 cells (IC50=2.5uM). Reported to be a more potent and selective inhibitor than Y-27632. Alternate Names: H-1152, H-1152P, (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine, 2HCl, ROCK Inhibitor, Dimethylfasudil (diMF, H-1152P) Formula: C16H21N3O2S • 2HCl Solubility: H2O (5mg/ml) or Methanol (5mg/ml) |
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| Size | 1mg, 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Rho Kinase Inhibitor (H-1152, H-1152P, (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine, 2HCl, ROCK Inhibitor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 29603 |
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| Price | |
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| Order / More Info | Rho Kinase Inhibitor from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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