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| Product Name | CREG, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). Cellular repressor of E1A-stimulated genes (CREG) is a 28-33kD member of the CREG family of proteins. Mouse CREG is synthesized as a 220aa precursor that contains a 31 aa signal sequence and a 189 aa mature chain (SwissProt # O88668) (1, 2). Mass spectrometric analysis of recombinant CREG revealed that the protein contains phosphorylated oligosaccharides at either of its two N-glycosylation sites (1). Mouse CREG shares 78% aa sequence identity with human CREG. CREG is a secreted glycoprotein ubiquitously expressed in mammals (3). It is largely secreted by fibroblasts missing both mannose 6-phosphate receptors (1). This is not observed in cells lacking only one of them (1). CREG is proposed to participate in a wide range of cellular processes. Among them, CREG has been found to antagonize transcriptional and cellular transformation by the adenoviral E1A oncoprotein (1, 3, 4), to induce differentiation while attenuating cellular proliferation (1, 3, 4, 5), to regu |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CREG, Recombinant, Mouse (Cellular Repressor of E1A-stimulated Genes 1, CREG 1, CREG, Protein CREG1) |
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| Gene, Accession, CAS # | Accession: NP_035934 |
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| Catalog # | C7918-70C |
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| Order / More Info | CREG, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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