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| Product Name | CRELD1, Recombinant, Mouse (Cysteine-rich Protein With EGF-like Domains 1, AVSD2) |
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| Description | Purity ~95% (SDS-PAGE). Cysteinerich with EGFlike domain protein 1 (CRELD1) is an ~50kD transmembrane glycoprotein that contains a 333aa extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15aa (1). Within the large ECD, mouse and human CRELD1 share 92%aa sequence identity. CRELD1 is widely expressed during development and in the adult (1). It interacts with Reticulon 3/RTN3 and inhibits the proapoptotic activity of RTN3 (2). CRELD1 also associates with Adrenergic alpha1 receptors in the prostate and limits their expression (3). Missense mutations of human CRELD1 are associated with susceptibility to atrioventricular septal defects in the heart (4). Source: Recombinant corresponding to aa30362 from mouse CRELD1 at C-terminal, expressed in NS0 cells (Q91XD7). Molecular Weight: ~37.1kD Biological Activity: Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. The ED50 for this effect is typically 0.3-1.5ug/ml. Endotoxin: <0.10 E |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 167641 |
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| Order / More Info | CRELD1, Recombinant, Mouse (Cysteine-rich Protein With EGF-like Domains 1, AVSD2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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