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| Product Name | Ngfb, Recombinant, Mouse (Beta-nerve Growth Factor, Beta-NGF, Ngf) |
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| Description | Purity ~98% (SDS-PAGE and HPLC). Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor Beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of murine Beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.4kD polypeptide monomers (240aa). The three disulfide bonds are required for biological activity. Source: Recombinant protein corresponding to mouse NGF beta, expressed in E.coli. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The ED50 was found to be <1ng/ml. Sspecific Activity: 1x10e6units/mg Endotoxin: <0.1ng/ug (1EU/u |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149733 |
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| Order / More Info | Ngfb, Recombinant, Mouse (Beta-nerve Growth Factor, Beta-NGF, Ngf) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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