| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Dual specificity protein phosphatase 26 |
|---|
| Description | 1-211aa; Full Length. MW: 39.93kD. Purity >90% as determined by SDS-PAGE. Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |
|---|
| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [Dual specificity phosphatase SKRP3; Low-molecular-mass dual-specificity phosphatase 4; DSP-4; LDP-4; Mitogen-activated protein kinase phosphatase 8; MAP kinase phosphatase 8; MKP-8; Novel amplified gene in thyroid anaplastic cancer] |
|---|
| Gene, Accession, CAS # | DUSP26, Gene ID: 78986, Accession: NP_001292044.1 |
|---|
| Catalog # | MBS1350791 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Dual specificity protein phosphatase 26 from MYBIOSOURCE INC. |
|---|
| Product Specific References | MKP-8, a novel MAPK phosphatase that inhibits p38 kinase.Vasudevan S.A., Skoko J., Wang K., Burlingame S.M., Patel P.N., Lazo J.S., Nuchtern J.G., Yang J.Biochem. Biophys. Res. Commun. 330:511-518(2005) A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity.Yu W., Imoto I., Inoue J., Onda M., Emi M., Inazawa J.Oncogene 26:1178-1187(2007) Characterization of a novel low-molecular-mass dual specificity phosphatase-4 (LDP-4) expressed in |
|---|
| 产品资料 |
|
|