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| Antigenic Specificity | Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (aa 1-17), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The human CDC25 tyrosine phosphatases trigger activation of CDC2 by removing inhibitory phosphate from tyrosine and threonine residues of the cyclin-dependent kinases. The genes encoding these phosphatases are suspected of being potential oncogenes because of their role in promoting cell division. Three human CDC25 genes have been identified: CDC25A, CDC25B, and CDC25C. The CDC25A gene is mapped to 3p21. In rodent cells, human CDC25A or CDC25B but not CDC25C phosphatases cooperate with either the gly12-to-val mutation of the HRAS gene or loss of RB1 in oncogenic focus formation. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Cdc25A(1-17aa MELGPEPPHRRRLLFAC), identical to the related rat and mouse sequences. |
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| Other Names | cdc25a2|cdc25A|sb:cb317|CDC25A2|D9Ertd393e |
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| Gene, Accession # | Gene ID: 993,171102 |
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| Catalog # | ABIN1706145 |
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| Price | |
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| Order / More Info | Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (aa 1-17), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 8276402, 7667636 |
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