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| Product Name | Fgr, active, Recombinant, Human |
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| Description | Purity ≥ 90% as determined by SDS-PAGE analysis. FGR is a proto-oncogene and a unique member of the tyrosine kinase family (1). Certain lymphomas (but not sarcomas or carcinomas) express FGR-related mRNA. This transcript is detected in Burkitt's lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt's lymphoma cells (2). Normal umbilical cord or peripheral blood lymphocyte lines established in vitro by EBV infection also contain detectable c-FGR mRNA. Moreover, a 50-fold increase of the steady-state c-FGR mRNA concentration is observed when uninfected Burkitt's lymphoma cell lines are deliberately infected with EBV demonstrating the induction of a proto-oncogene in response to infection by a DNA tumor virus. FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-FGR mRNA per cell (3). Very low levels of FGR transcripts are also present in U937 promo |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Fgr, active, Recombinant, Human (SRC2, c-FGR, p55 c-fgr, Human Gardner-Rasheed feline viral oncogene) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | F4149-08 |
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| Order / More Info | Fgr, active, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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