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| Product Name | PRL-1, aa2-173, catalytic domain, Recombinant, Human |
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| Description | Catalytic domain, (a.a. 1-173), MW=19.7kD, expressed in an E.coli expression system. The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. Application: useful for the study of enzyme kinetics, regulation, to dephosphorylate target substrates and for screening inhibitors. Purity: ≥95% by SDS-PAGE. Specific Activity: 0.45 U/ug. One unit will hydrolyze |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PRL-1, aa2-173, catalytic domain, Recombinant, Human (Protein tyrosine phosphatase, Phosphatase of regenerating liver-1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9003-68 |
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| Order / More Info | PRL-1, aa2-173, catalytic domain, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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