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| Product Name | BMP-10, Recombinant, Human |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. Bone morphogenetic proteins(BMPs) constitute a subfamily within the TGF-beta superfamily of structurallyrelated signaling proteins. Members of this superfamily are widely distributedthroughout the body and are involved in diverse physiological processes duringboth pre- and postnatal life.ampnbsp BMP-10 plays a crucial role in thedevelopment of the embryonic heart by acting to stimulate and maintain cardiomyocyteproliferation.ampnbsp It can signal through various receptor complexes usuallycontaining BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10with its specific receptors can induce signaling initiated by thephosphorylation of SMAD transcription factors, including SMAD1, SMAD5, orSMAD8, but can also induce SMAD independent processes.ampnbsp BMP-10 is structurallyrelated to BMP-9, and both can inhibit endothelial cell proliferation andmigration.ampnbsp Recombinant human BMP-10 is a24.4kD homodimeric disulfide-linked protein |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143291 |
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| Order / More Info | BMP-10, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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