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| Product Name | NUAK1, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). NUAK1 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 1 that is also known as AMPK-related protein kinase 5 (ARK5). ARK5 is a tumor cell survival factor that is activated by AKT and acts as an ATM kinase under conditions of nutrient starvation. NUAK1 is highly expressed in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung, and liver. NUAK1 is involved in tolerance to glucose starvation and suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR. Source: Recombinant protein corresponding to human NUAK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~122kD Specific Activity: 50nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NUAK1, Recombinant, Human, GST-Tag (NUAK Family SNF1-like Kinase 1, AMPK-related Protein Kinase 5, Omphalocele Kinase 1, ARK5, KIAA0537) |
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| Gene, Accession, CAS # | Accession: NM_014840 |
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| Catalog # | 500322 |
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| Order / More Info | NUAK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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