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| Product Name | SB-743921 (hydrochloride) |
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| Description | An Eg5 inhibitor (Ki = 0.5 nM for microtubule-stimulated ATPase activity); inhibits the growth of various cancer cell lines in vitro (GI50s = 22-82 nM); induces complete tumor regression in a COLO 205 mouse xenograft model and partial regression in MCF-7, SK-MES, H69, and OVCAR-3 mouse xenograft models; reduces tumor volume in a DLBCL mouse xenograft model from 2.5-10 mg/kg |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 618430-39-0 SB743921 Eg-5 HCT-116 PC-3 K-562 BxPC3 NCIH1299 COLO205 MCF7 SKMES H-69 OVCAR3 SB-91 SB91 |
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| Gene, Accession, CAS # | CAS: 940929-33-9 |
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| Catalog # | 18384-10 |
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| Price | |
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| Order / More Info | SB-743921 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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