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| Product Name | TNF-b, Human, BioAssay™ ELISA Kit (Tumor Necrosis Factor beta) |
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| Description | TNF-beta (TNF-b) is a protein of 171 amino acids in length and N-glycosylated at position 62. Some cell lines secrete varying glycosylated forms of the factor that may differ also in their biological activities. The protein does not contain disulfide bonds and forms heteromers with LT-beta (Lymphotoxin-beta) that anchors the complexes in the membrane. TNF-b and TNF-a show ~30 percent sequence homology and bind to the same receptor, and murine and human TNF-bare highly homologous at 74 percent. The biological functions of human TNF-b(hTNF-b) include promoting lymphoid development, enhancing normal host resistance to infection, and inhibiting growth of malignant tumors. Elevated hTNF-b levels are usually related to Crohn's Disease, multiple sclerosis, juvenile rheumatoid adrenoleucodystrophy, hypercalcemia of adult T cell leukemia, arthritis, bulbous pemphigoid, non-Hodgkin's lymphoma, and pregnancy. TNF-b is cytolytic or cytostatic for many tumor cells and acts as a mitogen for B-lympho |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 216059 |
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| Order / More Info | TNF-b, Human, BioAssay™ ELISA Kit (Tumor Necrosis Factor beta) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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