| 产品详情 |
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| Product Name | NSC-59984 |
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| Description | Purity >98% by HPLC. NSC-59984 is a p53 pathway activator that induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC50 of NSC-59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 MM for p53-null HCT116 cells. NSC-59984 induces p73-dependent cell apoptosis in cancer in vivo. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (E)-1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one |
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| Gene, Accession, CAS # | CAS: 803647-40-7 |
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| Catalog # | LS-H3764 |
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| Order / More Info | NSC-59984 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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