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| Product Name | NSC663284 |
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| Description | Purity >98% by NMR, TLC. NSC663284 is a potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. NSC663284 acts via irreversible oxidation of the catalytic cysteine of CDC254. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
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| Gene, Accession, CAS # | CAS: 383907-43-5 |
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| Catalog # | LS-H14532 |
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| Order / More Info | NSC663284 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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