| 产品详情 |
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| Product Name | NSC-697923 |
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| Description | Purity >98% by NMR, TLC. NSC-69723 is a selective inhibitor of E2 ubiquitin-conjugating enzyme, Ubc13-Uev1A. Does not inhibit UbcH5c activity. Impedes the formation of the Ubc13 and inhibits NF-kB activation in activated B cell-like diffuse large B-cell lymphoma (ABC-DLBCL) cells. Blocks proliferation and survival of both ABC-DLBCL and germinal center B cell-like (GCB)-DLBCL cell lines, and survival of primary DLBCL cells. NSC-69723 acts via covalent bonding to E2 active site thiol. Induces neuroblastoma cell death via activation of p53 and JNK. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(Methylphenyl)sulfonyl]-5-nitrofuran |
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| Gene, Accession, CAS # | CAS: 343351-67-7 |
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| Catalog # | LS-H14788 |
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| Order / More Info | NSC-697923 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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