| 产品详情 |
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| Product Name | Protein X, Recombinant, Hepatitis B Virus, aa1-154, His-SUMO-Tag (Genotype D subtype ayw, X) |
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| Description | Purity ~90% (SDS-PAGE). Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contai |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HBx Peptide X pX |
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| Gene, Accession, CAS # | SwissProt: P03165 |
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| Catalog # | 374886 |
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| Order / More Info | Protein X, Recombinant, Hepatitis B Virus, aa1-154, His-SUMO-Tag (Genotype D subtype ayw, X) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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