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| Product Name | Protein Z |
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| Description | Purity ~98% SDS-PAGE. Human protein Z is prepared from fresh frozen plasma similar to the procedure described by Broze and Miletich. Human protein Z (PZ) is a single chain, vitamin K-dependent plasma protein. Analogous with the majority of the coagulation proteins, protein Z is synthesized in the liver. The mature protein contains 360 amino acids. Based on amino acid sequence homology the domain structure is similar to that of other vitamin K-dependent zymogens which include factor VII, factor IX, factor X, and protein C. The N-terminal region contains a carboxyglutamic acid (Gla) domain important in its phospholipid membrane binding ability. Following the N-terminal Gla domain are two EGF domains and a region which connects to a catalytic-like domain. The C-terminal region has been shown to lack the ``typical'' serine protease activation site as well as the His and Ser residues from the catalytic triad. Protease activity has not been detected in either the full-length protein or cleavag |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P9109-50 |
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| Order / More Info | Protein Z from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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