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| Product Name | Rantes, Recombinant, Human (Regulated on Activation, Normal T-cell Expressed and Secreted, CCL5) |
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| Description | Purity ~95% (RP-HPLC, SDS-PAGE). Regulated upon Activation, Normal T-cell expressed, and Secreted or RANTES is an 8kD protein classified as a chemotactic cytokine or chemokine. It has recently been renamed CCL5. RANTES is chemotactic for T cells, eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e. IL-2and IFN-gamma) that are released by T cells, RANTES also induces the proliferation and activation of certain natural killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. It is also a HIV- suppressive factor released from CD8+ T cells. This chemokine has been localized to chromosome 17 in humans. Source: Recombinant protein corresponding to a single, non-glycosylated polypeptide chain containing 68aa from human Rantes, expressed in E. coli. Molecular Weight: ~7.8kD Biological Activity: Determined by the dose dependent chemotaxis of THP-1 cells. ED50 range=5.0-20ng/ml. |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209168 |
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| Order / More Info | Rantes, Recombinant, Human (Regulated on Activation, Normal T-cell Expressed and Secreted, CCL5) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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