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| Product Name | RAP1A, aa1-181, Recombinant, Human |
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| Description | Purity ~85% (SDS-PAGE). Ras-related protein Rap-1A (RAP1A) belongs to the family of RAS-related proteins. These proteins share approximately 50% aa identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st aa: glutamine in RAS is replaced by threonine in RAP proteins. This Protein Induces morphological reversion of a cell line transformed by a Ras oncogene and Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Source: Recombinant corresponding to aa1-181 of human HRAS, 6x His tagged, expressed in E.coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDCQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTEDVP MILVGNKCDL EDERVVGKEQ GQNLARQWCN CAFLESSAKS KINVNEIFYD LVRQINRKTP VEKKKPKKKS C Molecular Weight: 22.8kD (201aa), confirmed by MALDI-T |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RAP1A, aa1-181, Recombinant, Human (Ras-related Protein Rap-1A, C21KG, G-22K, Krev-1, Ras-related Protein Krev-1, KREV1) |
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| Gene, Accession, CAS # | Accession: NP_001010935 |
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| Catalog # | R1120-19 |
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| Order / More Info | RAP1A, aa1-181, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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