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| Product Name | SIRT4 Recombinant protein |
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| Description | MW: ~62 kDa. Full-length recombinant human SIRT4 was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: SIRT4 is a member of the sirtuin family of proteins which are homologs to the yeast Sir2 protein. Sirtuin family contain a sirtuin core domain and are grouped into four classes with SIRT4 being a member of class IV. SIRT4 lacks deacetylase activity but has ADP-ribosyltransferase activity (1). Immunoprecipitation analysis shows that SIRT4 interacts with |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [IR2L4; MGC57437; MGC130046; MGC130047; sirtuin 4] |
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| Gene, Accession, CAS # | SIRT4, Gene ID: 23409, Accession: NP_036372.1 |
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| Catalog # | MBS515139 |
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| Order / More Info | SIRT4 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Frye, R. A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260: 273-279, 1999. 2. Haigis, M. C. et al: SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126: 941-954, 2006. |
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