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| Product Name | Leptin Receptor Gene Related Protein, Human Control Peptide (OBGRP) |
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| Description | Highly purified. A 15 amino acid sequence within the first putative intracellular domain of human of human OB-RGRP (1) was coupled to KLH and antibodies generated in rabbits. Obesity, a common nutritional disorder, is associated with diabetes, hypertension, hyperlipidemia, cancer and many other health related problems. At least five genes, Obese (ob), diabetes (db), fat (fat), agouti yellow (Ay), and tubby (tub) have been linked to obesity. Obese gene encodes an adipocyte-tissue derived secreted protein Ob protein/Leptin (167 amino acid, ~16kD) that controls body weight homeostasis. Leptin mediates its effects via the Leptin receptor or Obese receptors (OBR or LR) that is expressed in several tissues including hypothalamus. The Ob-R has at least 6 alternatively spliced forms (OBRa-f or LRa-f) that contain a common extracellular domain. The OBRa represents the initially identified mouse Ob-R (short form, 894aa). OBRa, -c, -d, and -f differ in sequence after Lys889 and have short (30-40 |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1671-24B |
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| Order / More Info | Leptin Receptor Gene Related Protein, Human Control Peptide (OBGRP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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