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| Product Name | Leptin Receptor, Mouse, Control Peptide (OBR, LEPR, B219, Obese Receptor) |
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| Description | Highly purified. Control Peptide for L1671-09A (antiserum) and L1671-09 (affinity purified) A 15 amino acid sequence near the N-terminus (extracellular domain) of mouse OBR was selected for antibody production. Obesity, a common nutritional disorder, is associated with diabetes, hypertension, hyperlipidemia, cancer and many other health related problems. At least five genes, Obese (ob), diabetes (db), fat (fat), agouti yellow (Ay), and tubby (tub) have been linked to obesity. Obese gene encodes an adipocyte-tissue derived secreted protein Ob protein/Leptin (146 amino acid, ~16kD) that controls body weight homeostasis. Leptin mediates its effects via the Leptin receptor or Obese receptors (OBR or LEPR) that is expressed in several tissues including hypothalamus. The Ob-R has at least 6 alternatively spliced forms (OBRa-f or LRa-f) that contain a common extracellular domain. The OBRa represents the initially identified mouse Ob-R (short form, 894aa). OBRa, -c, -d, and -f differ in sequen |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1671-09B |
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| Order / More Info | Leptin Receptor, Mouse, Control Peptide (OBR, LEPR, B219, Obese Receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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