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| Product Name | Leptin Receptor, Mouse (OBR, LEPR, B219, Obese Receptor) (Control Peptide) |
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| Description | Highly purified. Control Peptide for L1671-11A (antiserum) and L1671-11 (affinity purified) antibodies. Obesity, a common nutritional disorder, is associated with diabetes, hypertension, hyperlipidemia, cancer and many other health related problems. At least five genes, Obese (ob), diabetes (db), fat (fat), agouti yellow (Ay), and tubby (tub) have been linked to obesity. Obese gene encodes an adipocyte-tissue derived secreted protein Ob protein/Leptin (146 amino acid, ~16kD) that controls body weight homeostasis. Leptin mediates its effects via the Leptin receptor or Obese receptors (OBR or LEPR) that is expressed in several tissues including hypothalamus. The Ob-R has at least 6 alternatively spliced forms (OBRa-f or LRa-f) that contain a common extracellular domain. The OBRa represents the initially identified mouse Ob-R (short form, 894aa). OBRa, -c, -d, and -f differ in sequence after Lys889 and have short (30-40 aa) cytoplasmic extension Mouse Ob-Rb (long form) displays ~78% homol |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1671-11B |
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| Order / More Info | Leptin Receptor, Mouse (OBR, LEPR, B219, Obese Receptor) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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